bedGraph To BigWig

# 获取程序
wget http://hgdownload.cse.ucsc.edu/admin/exe/linux.x86_64/bedGraphToBigWig
# 加执行权限
chmod +x bedGraphToBigWig
# 将该文件移入PATH路径中，即可执行
mv bedGraphToBigWig ~/bin/

~/bin/bedGraphToBigWig insulation.bdg ~/Documents/ref/chrom_GRCh38.105.sizes insulation.bw

head ~/Documents/ref/chrom_GRCh38.105.sizes

chr1    248956422
chr2    242193529
chr3    198295559
chr4    190214555
chr5    181538259

head insulation.bdg

chr1    0   10000   1
chr1    10000   20000   0
chr1    20000   30000   3
chr1    30000   40000   10
chr1    40000   50000   11

ref

• https://open.bioqueue.org/home/knowledge/knowledgeSearchEngine/cat/39

• https://genomebrowser.wustl.edu/goldenPath/help/bigWig.html